Multipoint gene mapping using seriation. II. Analysis of simulated and empirical data.

@article{Buetow1987MultipointGM,
  title={Multipoint gene mapping using seriation. II. Analysis of simulated and empirical data.},
  author={Kenneth H. Buetow and Aravinda Chakravarti},
  journal={American journal of human genetics},
  year={1987},
  volume={41 2},
  pages={189-201}
}
Seriation methods provide an accurate and efficient means of constructing preliminary multilocus genetic maps. By using both simulated and previously published empirical data, multipoint mapping by seriation was critically evaluated. Analysis of the simulated data sets showed that the seriation methodology could accurately estimate order and interlocus distances. Application to the empirical data demonstrated that seriation could obtain results directly comparable with those of other multipoint… CONTINUE READING