Multiplication of Tubercle Bacilli within Mononuclear Phagocytes in Tissue Cultures Derived from Normal Animals and Animals Vaccinated with Bcg

  • Emanuel Suter
  • Published 1953 in The Journal of experimental medicine


When monocytes derived from normal guinea pigs or rabbits were infected with tubercle bacilli and cultivated in vitro, the bacilli multiplied abundantly within the cytoplasm of these cells. By contrast, intracellular multiplication of the bacilli was retarded or completely inhibited within the monocytes of rabbits or guinea pigs vaccinated with BCG. This… (More)


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