Multiplexing oscillatory biochemical signals.

  title={Multiplexing oscillatory biochemical signals.},
  author={Wiet Hendrik de Ronde and Pieter Rein ten Wolde},
  journal={Physical biology},
  volume={11 2},
In recent years it has been increasingly recognized that biochemical signals are not necessarily constant in time and that the temporal dynamics of a signal can be the information carrier. Moreover, it is now well established that the protein signaling network of living cells has a bow-tie structure and that components are often shared between different signaling pathways. Here we show by mathematical modeling that living cells can multiplex a constant and an oscillatory signal: they can… CONTINUE READING
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