Multiplexed measurement of serum antibodies using an array biosensor.

  title={Multiplexed measurement of serum antibodies using an array biosensor.},
  author={Mar{\'i}a Cruz Moreno-Bondi and Chris Rowe Taitt and Lisa C. Shriver-Lake and Frances S. Ligler},
  journal={Biosensors & bioelectronics},
  volume={21 10},
The array biosensor provides the capability for simultaneously measuring titers of antibody against multiple antigens. Human antibodies against four different targets, tetanus toxin, diphtheria toxin, staphylococcal enterotoxin B (SEB) and hepatitis B, were measured simultaneously in sera from eight different donors in a single assay and titers were determined. The assays could measure amounts of bound antibody as low as approximately 100 fg. Each individual serum exhibited a different pattern… CONTINUE READING

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