Multiplexed electrical detection of cancer markers with nanowire sensor arrays
@article{Zheng2005MultiplexedED, title={Multiplexed electrical detection of cancer markers with nanowire sensor arrays}, author={Gengfeng Zheng and Fernando Patolsky and Yi Cui and Wayne U. Wang and Charles M. Lieber}, journal={Nature Biotechnology}, year={2005}, volume={23}, pages={1294-1301} }
We describe highly sensitive, label-free, multiplexed electrical detection of cancer markers using silicon-nanowire field-effect devices in which distinct nanowires and surface receptors are incorporated into arrays. [] Key Result Protein markers were routinely detected at femtomolar concentrations with high selectivity, and simultaneous incorporation of control nanowires enabled discrimination against false positives.
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