Multiplexed Epitope-Based Tissue Imaging for Discovery and Healthcare Applications.

  title={Multiplexed Epitope-Based Tissue Imaging for Discovery and Healthcare Applications.},
  author={Bernd Bodenmiller},
  journal={Cell systems},
  volume={2 4},
The study of organs and tissues on a molecular level is necessary as we seek an understanding of health and disease. Over the last few years, powerful highly multiplexed epitope-based imaging approaches that rely on the serial imaging of tissues with fluorescently labeled antibodies and the simultaneous analysis using metal-labeled antibodies have emerged. These techniques enable analysis of dozens of epitopes in thousands of cells in a single experiment providing a systems level view of normal… CONTINUE READING
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