Multiplexed Echo Planar Imaging for Sub-Second Whole Brain FMRI and Fast Diffusion Imaging

  title={Multiplexed Echo Planar Imaging for Sub-Second Whole Brain FMRI and Fast Diffusion Imaging},
  author={David A. Feinberg and Steen Moeller and Stephen M. Smith and Edward J. Auerbach and Sudhir Ramanna and Matthew F. Glasser and Karla L. Miller and K{\^a}mil Uğurbil and Essa Yacoub},
  journal={PLoS ONE},
Echo planar imaging (EPI) is an MRI technique of particular value to neuroscience, with its use for virtually all functional MRI (fMRI) and diffusion imaging of fiber connections in the human brain. EPI generates a single 2D image in a fraction of a second; however, it requires 2–3 seconds to acquire multi-slice whole brain coverage for fMRI and even longer for diffusion imaging. Here we report on a large reduction in EPI whole brain scan time at 3 and 7 Tesla, without significantly sacrificing… 

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