Multiplexed 3D FRET imaging in deep tissue of live embryos

Abstract

Current deep tissue microscopy techniques are mostly restricted to intensity mapping of fluorophores, which significantly limit their applications in investigating biochemical processes in vivo. We present a deep tissue multiplexed functional imaging method that probes multiple Förster resonant energy transfer (FRET) sensors in live embryos with high… (More)
DOI: 10.1038/srep13991

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