Multiplex serum cytokine immunoassay using nanoplasmonic biosensor microarrays.

  title={Multiplex serum cytokine immunoassay using nanoplasmonic biosensor microarrays.},
  author={Pengyu Chen and Meng Ting Chung and Walker M McHugh and Robert Nidetz and Yuwei Li and Jianping Fu and Timothy T Cornell and Thomas P. Shanley and Katsuo Kurabayashi},
  journal={ACS nano},
  volume={9 4},
Precise monitoring of the rapidly changing immune status during the course of a disease requires multiplex analysis of cytokines from frequently sampled human blood. However, the current lack of rapid, multiplex, and low volume assays makes immune monitoring for clinical decision-making (e.g., critically ill patients) impractical. Without such assays, immune monitoring is even virtually impossible for infants and neonates with infectious diseases and/or immune mediated disorders as access to… CONTINUE READING
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