Multiplex biomarker approach for determining risk of prostate-specific antigen-defined recurrence of prostate cancer.

@article{Rhodes2003MultiplexBA,
  title={Multiplex biomarker approach for determining risk of prostate-specific antigen-defined recurrence of prostate cancer.},
  author={Daniel R. Rhodes and Martin George Sanda and Arie P. Otte and Arul M. Chinnaiyan and Mark A. Rubin},
  journal={Journal of the National Cancer Institute},
  year={2003},
  volume={95 9},
  pages={661-8}
}
BACKGROUND Molecular signatures in cancer tissue may be useful for diagnosis and are associated with survival. We used results from high-density tissue microarrays (TMAs) to define combinations of candidate biomarkers associated with the rate of prostate cancer progression after radical prostatectomy that could identify patients at high risk for recurrence. METHODS Fourteen candidate biomarkers for prostate cancer for which antibodies are available included hepsin, pim-1 kinase, E-cadherin… CONTINUE READING