• DOI:10.1002/ELPS.200406129
Corpus ID: 44989190

Multiplex amplified product‐length polymorphism analysis of 36 mitochondrial single‐nucleotide polymorphisms for haplogrouping of East Asian populations

@article{Umetsu2005MultiplexAP,
  title={Multiplex amplified product‐length polymorphism analysis of 36 mitochondrial single‐nucleotide polymorphisms for haplogrouping of East Asian populations},
  author={K. Umetsu and M. Tanaka and I. Yuasa and N. Adachi and A. Miyoshi and S. Kashimura and Kyung Sook Park and Y. Wei and G. Watanabe and M. Osawa},
  journal={ELECTROPHORESIS},
  year={2005},
  volume={26}
}

K. Umetsu, M. Tanaka, +7 authors M. Osawa

Published 2005

Biology, Medicine

ELECTROPHORESIS

We present a reliable, rapid, and economical multiplex amplified product‐length polymorphism (APLP) method for analyzing the haplogroup‐diagnostic mitochondrial single‐nucleotide polymorphisms (mtSNPs) in East Asian populations. By examining only 36 haplogroup‐specific mtSNPs in the coding region by using four 9‐multiplex polymerase chain reaction (PCR) and subsequent electrophoresis, we could safely assign 1815 individuals from 8 populations of Japanese, Korean, Chinese, and Germans to 45… CONTINUE READING

View on Wiley

ncbi.nlm.nih.gov

Save to Library

Create Alert

Cite

Launch Research Feed