Multiplex Genotyping of Cytokine Gene SNPs Using Fluorescence Bead Array

@inproceedings{Jang2015MultiplexGO,
  title={Multiplex Genotyping of Cytokine Gene SNPs Using Fluorescence Bead Array},
  author={Jung-Pil Jang and In-Cheol Baek and Eun-jeong Choi and Tai-Gyu Kim},
  booktitle={PloS one},
  year={2015}
}
Single nucleotide polymorphisms (SNPs) of genes that affect cytokine production and function are known to influence the susceptibility and progression of immune-related conditions such as infection, autoimmune diseases, transplantation, and cancer. We established a multiplex genotyping method to analyze the SNPs of cytokine genes by combining the multiplex PCR and bead array platform. Thirteen cytokine gene regions, including 20 SNPs, were amplified, and allele-specific primer extension was… CONTINUE READING

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