Multiple tissue-specific requirements for the BMP antagonist Noggin in development of the mammalian craniofacial skeleton.

@article{Matsui2014MultipleTR,
  title={Multiple tissue-specific requirements for the BMP antagonist Noggin in development of the mammalian craniofacial skeleton.},
  author={Maiko Matsui and John Klingensmith},
  journal={Developmental biology},
  year={2014},
  volume={392 2},
  pages={168-81}
}
Proper morphogenesis is essential for both form and function of the mammalian craniofacial skeleton, which consists of more than twenty small cartilages and bones. Skeletal elements that support the oral cavity are derived from cranial neural crest cells (NCCs) that develop in the maxillary and mandibular buds of pharyngeal arch 1 (PA1). Bone Morphogenetic Protein (BMP) signaling has been implicated in most aspects of craniofacial skeletogenesis, including PA1 development. However, the roles of… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 67 references

palate formation and delayed tooth differentiation

  • J. Klingensmith
  • PloS One
  • 2013
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