• Computer Science, Medicine
  • Published in Statistics in medicine 2013
  • DOI:10.1002/sim.5976

Multiple time scales in multi-state models.

@article{Iacobelli2013MultipleTS,
  title={Multiple time scales in multi-state models.},
  author={Simona Iacobelli and Bendix Carstensen},
  journal={Statistics in medicine},
  year={2013},
  volume={32 30},
  pages={
          5315-27
        }
}
In multi-state models, it has been the tradition to model all transition intensities on one time scale, usually the time since entry into the study ('clock-forward' approach). The effect of time since an intermediate event has been accommodated either by changing the time scale to time since entry to the new state ('clock-back' approach) or by including the time at entry to the new state as a covariate. In this paper, we argue that the choice of time scale for the various transitions in a multi… CONTINUE READING

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