Multiple system organ response induced by hyperoxia in a clinically relevant animal model of sepsis.


Oxygen therapy is currently used as a supportive treatment in septic patients to improve tissue oxygenation. However, oxygen can exert deleterious effects on the inflammatory response triggered by infection. We postulated that the use of high oxygen concentrations may be partially responsible for the worsening of sepsis-induced multiple system organ… (More)
DOI: 10.1097/SHK.0000000000000189


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