Multiple system atrophy: a review of 203 pathologically proven cases.

  title={Multiple system atrophy: a review of 203 pathologically proven cases.},
  author={Gregor Karl Wenning and Francois Tison and Y Ben Shlomo and Susan E Daniel and Niall Quinn},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  volume={12 2},
We report the clinicopathological features of 203 cases of pathologically proven multiple system atrophy (MSA) from 108 publications up to February 1995. The majority of patients showed symptoms in their early fifties, and men were more commonly affected than women (ratio of 1.3:1). Most patients suffered from some degree of autonomic failure (74%). Parkinsonism was the most common motor disorder (87%), followed by cerebellar ataxia (54%) and pyramidal signs (49%). The response to levodopa was… CONTINUE READING
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