Multiple-source current steering in subthalamic nucleus deep brain stimulation for Parkinson's disease (the VANTAGE study): a non-randomised, prospective, multicentre, open-label study

@article{Timmermann2015MultiplesourceCS,
  title={Multiple-source current steering in subthalamic nucleus deep brain stimulation for Parkinson's disease (the VANTAGE study): a non-randomised, prospective, multicentre, open-label study},
  author={Lars Timmermann and Roshini Jain and Lilly Chen and Mohamed Maarouf and Francois Alesch},
  journal={The Lancet Neurology},
  year={2015},
  volume={14},
  pages={693-701}
}
BACKGROUND High-frequency deep brain stimulation (DBS) with a single electrical source is effective for motor symptom relief in patients with Parkinson's disease. We postulated that a multiple-source, constant-current device that permits well defined distribution of current would lead to motor improvement in patients with Parkinson's disease. METHODS We did a prospective, multicentre, non-randomised, open-label intervention study of an implantable DBS device (the VANTAGE study) at six… CONTINUE READING

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