Multiple somatotopic representations of heat and mechanical pain in the operculo-insular cortex: a high-resolution fMRI study.

@article{Baumgrtner2010MultipleSR,
  title={Multiple somatotopic representations of heat and mechanical pain in the operculo-insular cortex: a high-resolution fMRI study.},
  author={U. Baumg{\"a}rtner and Gian Domenico Iannetti and Laura Zambreanu and Peter Stoeter and Rolf-Detlef Treede and Irene Tracey},
  journal={Journal of neurophysiology},
  year={2010},
  volume={104 5},
  pages={2863-72}
}
Whereas studies of somatotopic representation of touch have been useful to distinguish multiple somatosensory areas within primary (SI) and secondary (SII) somatosensory cortex regions, no such analysis exists for the representation of pain across nociceptive modalities. Here we investigated somatotopy in the operculo-insular cortex with noxious heat and pinprick stimuli in 11 healthy subjects using high-resolution (2 × 2 × 4 mm) 3T functional magnetic resonance imaging (fMRI). Heat stimuli… CONTINUE READING

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