Multiple-site labeling of proteins with unnatural amino acids.


The advent of efficient systems using genetic encoding for the site-specific incorporation of unnatural amino acids (UAA) into proteins has opened countless new possibilities for studying the structure, dynamics, and interactions of proteins. In particular, orthogonal pairs of amber suppressor tRNA (MjtRNA) and tyrosyl-tRNA synthetase (MjTyrRS) of… (More)
DOI: 10.1002/anie.201108275


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