Multiple signalling options for prostacyclin.

  title={Multiple signalling options for prostacyclin.},
  author={Helen Wise},
  journal={Acta pharmacologica Sinica},
  volume={24 7},
  • Helen Wise
  • Published 2003 in Acta pharmacologica Sinica
The fate of a cell following stimulation by the prostanoid prostacyclin is cell specific, depending not only on the ability of prostacyclin to activate the cell surface prostacyclin (IP) receptor and regulate its coupling to various G proteins, but also on its ability to act intracellularly via the nuclear peroxisome proliferator-activated receptor family (PPAR). This review will highlight the different signalling options available to prostacyclin, and discuss the consequences for cell… CONTINUE READING

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