Multiple signal pathways in obesity-associated cancer.

  title={Multiple signal pathways in obesity-associated cancer.},
  author={Jiezhong Chen},
  journal={Obesity reviews : an official journal of the International Association for the Study of Obesity},
  volume={12 12},
Obesity is increasing worldwide and reaches to a large proportion of the population in developed countries. Thus, obesity-associated cancer has become a major health problem. Multiple cancer risk factors in obesity have been identified including insulin/insulin-like growth factor axis, adipokines and cytokines; and multiple intracellular signal pathways have been studied. However, the role of each signal pathway in obesity-associated cancer is controversial. In this review, the recent studies… CONTINUE READING

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