Multiple sequence alignment.

  title={Multiple sequence alignment.},
  author={Robert C. Edgar and Serafim Batzoglou},
  journal={Current opinion in structural biology},
  volume={16 3},
Multiple sequence alignments are an essential tool for protein structure and function prediction, phylogeny inference and other common tasks in sequence analysis. Recently developed systems have advanced the state of the art with respect to accuracy, ability to scale to thousands of proteins and flexibility in comparing proteins that do not share the same domain architecture. New multiple alignment benchmark databases include PREFAB, SABMARK, OXBENCH and IRMBASE. Although CLUSTALW is still the… CONTINUE READING
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