Multiple sclerosis with very late onset.

@article{Hooge1992MultipleSW,
  title={Multiple sclerosis with very late onset.},
  author={John Hooge and W. Ken Redekop},
  journal={Neurology},
  year={1992},
  volume={42 10},
  pages={1907-10}
}
Multiple sclerosis (MS) can present clinically after age 59, but only rarely. In a large MS population (N = 2,019), 0.6% of patients had their first symptom at age 60 or older. Of this group, six had clinically definite MS, two had laboratory-supported definite MS, and four had clinically probable MS. The onset at this age was characteristically a slow deterioration of motor function. Most (10 of 12) of these very late-onset patients had a progressive course of disease from onset. 

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