Multiple sclerosis with and without CSF bands: Clinically indistinguishable but immunogenetically distinct

  title={Multiple sclerosis with and without CSF bands: Clinically indistinguishable but immunogenetically distinct},
  author={Kerstin Imrell and A.-M. Landtblom and Jan Hillert and Thomas Masterman},
  pages={1062 - 1064}
We sought to determine whether Swedish patients with multiple sclerosis (MS) with and without oligoclonal bands (OCBs) in the CSF constitute distinct subpopulations, clinically and immunogenetically. Our findings indicate that OCB-negative MS shares the same clinical features as OCB-positive MS regarding female predominance, age at onset, proportion of primary progressive cases, rate of MRI positivity, and disease severity. Our HLA-DRB1 genotyping results suggest, however, that OCB-positive and… 

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