Multiple sclerosis lesion formation and early evolution revisited: A weekly high-resolution magnetic resonance imaging study

@article{Guttmann2016MultipleSL,
  title={Multiple sclerosis lesion formation and early evolution revisited: A weekly high-resolution magnetic resonance imaging study},
  author={Charles R. G. Guttmann and Matthieu Rousset and J A Roch and Salem Hannoun and Françoise Durand-Dubief and Boubakeur Belaroussi and Michele Cavallari and Muriel Rabilloud and Dominique Sappey-Marinier and Sandra Vukusic and François Cotton},
  journal={Multiple Sclerosis Journal},
  year={2016},
  volume={22},
  pages={761 - 769}
}
Background: Several magnetic resonance imaging (MRI) studies investigated the evolution of multiple sclerosis (MS) lesions to understand the pathophysiological mechanisms leading to blood-brain barrier breakdown and lesion formation. Only a few assessed the early natural history of MS lesions using short-interval longitudinal MRI. Objective: The purpose of this study was to characterize MS lesion occurrence and early evolution on high-resolution MRI acquired at weekly intervals. Methods: Active… 
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