Multiple sclerosis-associated retrovirus in early multiple sclerosis: a six-year follow-up of a Sardinian cohort.

@article{Sotgiu2006MultipleSR,
  title={Multiple sclerosis-associated retrovirus in early multiple sclerosis: a six-year follow-up of a Sardinian cohort.},
  author={Stefano Sotgiu and Giannina Arru and Giuseppe Mameli and Caterina Canyelles Serra and Maura Pugliatti and G. Rosati and Antonina Dolei},
  journal={Multiple sclerosis},
  year={2006},
  volume={12 6},
  pages={
          698-703
        }
}
The human endogenous retroviruses (HERV)-W family contains an extracellular particle detected in multiple sclerosis (MS) patients and designated as MS-associated retrovirus (MSRV). Through nested RT-PCR assays specific for pol MSRV gene, we preliminary reported that its presence in the cerebrospinal fluid (CSF) of early MS patients could be indicative of a poor prognosis upon a three-year follow-up. In the present clinical study, we enlarged our blind observation up to six years. At study entry… CONTINUE READING
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