Multiple sclerosis as a vascular disease

  title={Multiple sclerosis as a vascular disease},
  author={Alireza Minagar and Wenche Jy and J. J. Jimenez and Jonathan Steven Alexander},
  journal={Neurological Research},
  pages={230 - 235}
Abstract Multiple sclerosis (MS) has traditionally been viewed and researched as an immune-mediated disease with principal emphasis on the role of activated inflammatory cells, oligodendrocytes and astrocytes in its pathogenesis. Abnormalities of cerebral endothelial cells (CECs) is an under explored facet of MS pathogenesis and vascular abnormalities play a crucial role in formation of the MS lesions and disease progress, at least in the initial stages of disease. This review will focus on MS… 
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