Multiple sclerosis

@article{Compston2008MultipleS,
  title={Multiple sclerosis},
  author={Alastair S. Compston and Alasdair J. Coles},
  journal={The Lancet},
  year={2008},
  volume={372},
  pages={1502-1517}
}

MAGNETIC RESONANCE SPECTROSCOPY OF NORMAL APPEARING WHITE MATTER IN EARLY RELAPSING-REMITTING MULTIPLE SCLEROSIS Enas

TLDR
This study carried out on 23 patients with clinically definite multiple sclerosis patients, and clearly demonstrated a correlation between an MRS measure and EDSS score, which seems to reflect the existence of irreversible disability probably related to axonal degeneration.

Detecting neurodegenerative pathology in multiple sclerosis before irreversible brain tissue loss sets in

TLDR
This Narrative Review focuses on alternative techniques with the potential of detecting neurodegenerative events in the brain of subjects with MS prior to the atrophic stage, and recent findings provide the promising prospect of demonstrating degenerative brain pathology in patients with MS before atrophy has installed.

The early diagnosis and treatments in multiple sclerosis

  • S. Huh
  • Medicine, Psychology
  • 2017
TLDR
A review looks at MS diagnostic criteria newly published in 2016 and highlights the importance of differential diagnosis and early treatment.

Pregnancy-Related Immune Changes and Demyelinating Diseases of the Central Nervous System

TLDR
Current knowledge on the immune status during pregnancy is summarized, the relationship between pregnancy-related immune changes and demyelinating diseases of the central nervous system is discussed, and the immune response of patients with autoimmune disease complicated with pregnancy is different.

Multiple sclerosis: clinical aspects

TLDR
The epidemiology, diagnosis, disease course, and prognosis of multiple sclerosis is discussed and a combination of clinical, imaging, and laboratory markers can be useful in predicting clinical course and optimizing treatment in individual patients.
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