Multiple sclerosis–associated retrovirus (MSRV) in Sardinian MS patients

  title={Multiple sclerosis–associated retrovirus (MSRV) in Sardinian MS patients},
  author={Antonina Dolei and Caterina Serra and Giuseppe Mameli and Maura Pugliatti and GianPietro Sechi and M C Cirotto and Giulio Rosati and Stefano Sotgiu},
Abstract—Blood and CSF of Sardinian patients with MS and neurologic control subjects were tested for MS-associated retrovirus (MSRV). CSF detection in MS was 50% at clinical onset, increasing with temporal disease progression, and 40% in control subjects. In blood, MSRV was detected in all MS patients, in most patients with inflammatory neurologic diseases, and rarely in healthy blood donors. MSRV may represent a marker of neurologic diseases of inflammatory origin. 

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