Multiple retiform hemangioendotheliomas. A low-grade angiosarcoma.

  title={Multiple retiform hemangioendotheliomas. A low-grade angiosarcoma.},
  author={Dennis Duke and Ann E. Dvorak and Terrell J. Harris and Lisa M. Cohen},
  journal={The American Journal of dermatopathology},
  volume={18 6},
We present the case of a 30-year-old woman who over a 10-year period has developed multiple well-differentiated angiosarcomas involving the trunk and extremities. The clinical and histologic features are characteristic of retiform hemangioendothelioma (RH), a distinctive form of low-grade angiosarcoma. This case is unique in that multiple lesions developed in different anatomic sites. We discuss the clinical and histologic characteristics, diagnosis, and prognosis of RH. 

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