Multiple resistance mechanisms in Chinese hamster cells resistant to 9-hydroxyellipticine.

@article{Larsen1989MultipleRM,
  title={Multiple resistance mechanisms in Chinese hamster cells resistant to 9-hydroxyellipticine.},
  author={Annette Kragh Larsen and Alain G Jacquemin-Sablon},
  journal={Cancer research},
  year={1989},
  volume={49 24 Pt 1},
  pages={7115-9}
}
We have previously shown that Chinese hamster lung cells resistant to 9-hydroxyellipticine, DC-3F/9-OH-E, display multiple phenotypical alterations including cross-resistance to a variety of drugs as well as loss of tumorigenicity. We now analyze a DC-3F/9-OH-E subline that has been maintained for a prolonged period of time in drug-free medium in order to clarify the relationships between the various phenotypic traits. The absence of selection resulted in a partial recovery of the ability to… CONTINUE READING

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References

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Showing 1-10 of 26 references

Effects of verapamil on the cellular accumulations and toxicity of several antitumor drugs in 9-hydroxy-ellipticine resistant cells

  • C Delaporte., Charcosset, J.-Y, A Jacquemin-Sablon.
  • Biochem. Pharmacol.,
  • 1988
Highly Influential
4 Excerpts

Role of the glutathione rcdox cycle in acquired and tie novo multidrug resistance

  • A Kramer.R., J. Zakher, G. Kim
  • Science (Wash DC),
  • 1988
1 Excerpt

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