Multiple protein sequence alignment.

  title={Multiple protein sequence alignment.},
  author={Jimin Pei},
  journal={Current opinion in structural biology},
  volume={18 3},
Multiple sequence alignments are essential in computational analysis of protein sequences and structures, with applications in structure modeling, functional site prediction, phylogenetic analysis and sequence database searching. Constructing accurate multiple alignments for divergent protein sequences remains a difficult computational task, and alignment speed becomes an issue for large sequence datasets. Here, I review methodologies and recent advances in the multiple protein sequence… CONTINUE READING

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