Multiple procyclin isoforms are expressed differentially during the development of insect forms of Trypanosoma brucei.

@article{Vassella2001MultiplePI,
  title={Multiple procyclin isoforms are expressed differentially during the development of insect forms of Trypanosoma brucei.},
  author={Erik Vassella and {\'A}lvaro Acosta-Serrano and Erwin Studer and Seok Ho Lee and Paul T. Englund and Isabel Roditi},
  journal={Journal of molecular biology},
  year={2001},
  volume={312 4},
  pages={597-607}
}
Transmission of Trypanosoma brucei by the tsetse fly entails several rounds of differentiation as the parasite migrates through the digestive tract to the salivary glands of its vector. Differentiation of the bloodstream to the procyclic form in the fly midgut is accompanied by the synthesis of a new coat consisting of EP and GPEET procyclins. There are three closely related EP isoforms, two of which (EP1 and EP3) contain N-glycans. To identify the individual EP isoforms that are expressed… CONTINUE READING
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