Multiple newly identified loci associated with prostate cancer susceptibility

@article{Eeles2008MultipleNI,
  title={Multiple newly identified loci associated with prostate cancer susceptibility},
  author={R. Eeles and Z. Kote-Jarai and G. Giles and Ali Amin Al Olama and M. Guy and S. Jugurnauth and S. Mulholland and D. Leongamornlert and S. Edwards and J. Morrison and H. Field and M. Southey and G. Severi and J. Donovan and F. Hamdy and D. Dearnaley and K. Muir and Charmaine D. Smith and M. Bagnato and A. Ardern-Jones and A. Hall and L. O'Brien and B. Gehr-Swain and R. Wilkinson and A. Cox and S. Lewis and Paul M. Brown and S. Jhavar and M. Tymrakiewicz and A. Lophatananon and Sarah L Bryant and A. Horwich and R. Huddart and V. Khoo and C. Parker and C. Woodhouse and A. Thompson and T. Christmas and C. Ogden and C. Fisher and C. Jamieson and C. Cooper and D. English and J. Hopper and D. Neal and D. Easton},
  journal={Nature Genetics},
  year={2008},
  volume={40},
  pages={316-321}
}
Prostate cancer is the most common cancer affecting males in developed countries. It shows consistent evidence of familial aggregation, but the causes of this aggregation are mostly unknown. To identify common alleles associated with prostate cancer risk, we conducted a genome-wide association study (GWAS) using blood DNA samples from 1,854 individuals with clinically detected prostate cancer diagnosed at ≤60 years or with a family history of disease, and 1,894 population-screened controls with… Expand
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