Multiple myeloma.

@article{Raab2009MultipleM,
  title={Multiple myeloma.},
  author={Marc S Raab and Klaus Podar and Iris Breitkreutz and Paul G Richardson and Kenneth C. Anderson},
  journal={Lancet},
  year={2009},
  volume={374 9686},
  pages={324-39}
}
Multiple myeloma is characterised by clonal proliferation of malignant plasma cells, and mounting evidence indicates that the bone marrow microenvironment of tumour cells has a pivotal role in myeloma pathogenesis. This knowledge has already expanded treatment options for patients with multiple myeloma. Prototypic drugs thalidomide, bortezomib, and lenalidomide have each been approved for the treatment of this disease by targeting both multiple myeloma cells and the bone marrow microenvironment… CONTINUE READING
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