Multiple myeloma presenting with an acute bacterial infection.

  title={Multiple myeloma presenting with an acute bacterial infection.},
  author={George N Kalambokis and Leonidas G Christou and Epameinondas Tsianos},
  journal={International journal of laboratory hematology},
  volume={31 4},
Increased susceptibility to bacterial infections is a common manifestation of multiple myeloma (MM), arising mainly from a defect in humoral immunity and is associated with major morbidity and mortality. The propensity to infection is increased in the first months after the initial diagnosis and in patients with renal dysfunction. Gram-positive infections, mainly pneumonia from Streptococcus pneumoniae, occur more frequently in patients with untreated disease while Gram-negative infections… CONTINUE READING