Multiple myeloma-associated amyloidosis is an independent high-risk prognostic factor

@article{VelaOjeda2008MultipleMA,
  title={Multiple myeloma-associated amyloidosis is an independent high-risk prognostic factor},
  author={Jorge Vela-Ojeda and Miriam Garc{\'i}a-Ruiz Esparza and Ysabel Padilla-Gonz{\'a}lez and Evelia S{\'a}nchez-Cort{\'e}s and Jaime Garc{\'i}a-Ch{\'a}vez and Laura Arcelia Montiel-Cervantes and E Reyes-Maldonado and Abraham Majluf-Cruz and Hector Mayani},
  journal={Annals of Hematology},
  year={2008},
  volume={88},
  pages={59-66}
}
Several prognostic factors have been recognized in patients with multiple myeloma (MM). Among the most important are: the serum levels of β2-microglobulin, albumin, and LDH; the labeling index; and an abnormal karyotype. Patients with amyloidosis (AL) have poor prognosis; however, little is known concerning the prognostic significance of AL associated to MM. In 201 consecutive patients with de novo MM, we performed a fat-pad biopsy needle aspiration (FPBNA) that was stained with Congo red… CONTINUE READING