Multiple members of a third subfamily of P-type ATPases identified by genomic sequences and ESTs.

  title={Multiple members of a third subfamily of P-type ATPases identified by genomic sequences and ESTs.},
  author={Margaret S. Halleck and Dharamveer Pradhan and Colin Blackman and Charlotte A Berkes and Paul Williamson and Robert A. Schlegel},
  journal={Genome research},
  volume={8 4},
The Saccharomyces cerevisiae genome contains five P-type ATPases divergent from both of the well-known subfamilies of these membrane ion transporters. This newly recognized third subfamily can be further divided into four classes of genes with nearly equal relatedness to each other. Genes of this new subfamily are also present and expressed in multicellular organisms such as Caenorhabditis elegans and mammals; some, but not all, can be assigned to the classes identified in yeast. Different… CONTINUE READING


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