Multiple mechanisms of ontogenic regulation of nuclear receptors during rat liver development.

@article{Balasubramaniyan2005MultipleMO,
  title={Multiple mechanisms of ontogenic regulation of nuclear receptors during rat liver development.},
  author={Natarajan Balasubramaniyan and Mohammad Shahid and Frederick J. Suchy and Meenakshisundaram Ananthanarayanan},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2005},
  volume={288 2},
  pages={G251-60}
}
Nuclear receptors (NRs) play pivotal roles in the regulation of genes contributing to hepatobiliary cholesterol and bile acid homeostasis. We have previously shown that transporters involved in bile formation are developmentally regulated and are poorly developed during the fetal stage, but their expression reached gradual maturity during the postnatal period. To define the molecular mechanisms underlying this regulation and the role that class II NRs and associated members [liver receptor… CONTINUE READING

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Differential expression of bile salt and organic anion transporters in developing rat liver

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