Multiple mechanisms contribute to the robust rapid gamma interferon response by CD8+ T cells during Listeria monocytogenes infection.

@article{Ghanem2009MultipleMC,
  title={Multiple mechanisms contribute to the robust rapid gamma interferon response by CD8+ T cells during Listeria monocytogenes infection.},
  author={Elsa N. Bou Ghanem and Denise S McElroy and Sarah E F D'Orazio},
  journal={Infection and immunity},
  year={2009},
  volume={77 4},
  pages={1492-501}
}
A subset of CD8+ T cells can rapidly secrete gamma interferon (IFN-gamma) in an antigen-independent and interleukin-12 (IL-12)- and IL-18-dependent manner within 16 h of infection with the intracellular bacterial pathogen Listeria monocytogenes. This rapid IFN-gamma response is robust enough to be detected directly ex vivo and is not observed following… CONTINUE READING