Multiple isolates and characteristics of human T-cell leukemia virus type II.

@article{Hall1992MultipleIA,
  title={Multiple isolates and characteristics of human T-cell leukemia virus type II.},
  author={William W. Hall and Hirotaka Takahashi and Chang Liu and Mark H Kaplan and O Scheewind and Shinji Ijichi and Kunio Nagashima and Robert C. Gallo},
  journal={Journal of virology},
  year={1992},
  volume={66 4},
  pages={2456-63}
}
Human T-cell leukemia (or lymphotropic) virus type II (HTLV-II) was isolated from eight HTLV-seropositive patients, six of whom were also infected with human immunodeficiency virus, by cocultivation of peripheral blood mononuclear cells (PBMCs) with BJAB, a continuous B-cell line. Restriction endonuclease mapping of the proviruses demonstrated consistent differences among isolates, and two distinct physical map patterns were observed. The results suggest the existence of two closely related… CONTINUE READING