Multiple isoforms of CD46 (membrane cofactor protein) serve as receptors for measles virus.

@article{Manchester1994MultipleIO,
  title={Multiple isoforms of CD46 (membrane cofactor protein) serve as receptors for measles virus.},
  author={M. Addison Manchester and M. Kathryn Liszewski and John P Atkinson and Michael B A Oldstone},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1994},
  volume={91 6},
  pages={2161-5}
}
Measles virus (MV) causes a productive infection in humans and certain simian hosts. Rodent cells such as Chinese hamster ovary (CHO) and murine cell lines normally resist MV infection. Human CD46, or membrane cofactor protein, a complement regulatory protein, recently has been reported as the cellular receptor for MV. Multiple isoforms of the CD46 protein exist; four of these isoforms are commonly expressed on human cells. Expression of each of the four isoforms in CHO cells followed by… CONTINUE READING

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