Multiple intravenous infusions of bone marrow mesenchymal stem cells reverse hyperglycemia in experimental type 2 diabetes rats.

@article{Hao2013MultipleII,
  title={Multiple intravenous infusions of bone marrow mesenchymal stem cells reverse hyperglycemia in experimental type 2 diabetes rats.},
  author={Haojie Hao and Jiejie Liu and Jing Shen and Yali Zhao and Huilin Liu and Qian Hou and Chuan Tong and Dongdong Ti and Liang Dong and Yu Cheng and Yiming Mu and Jian-ping Liu and Xiaobing Fu and Weidong Han},
  journal={Biochemical and biophysical research communications},
  year={2013},
  volume={436 3},
  pages={418-23}
}
The worldwide rapid increase in diabetes poses a significant challenge to current therapeutic approaches. Single-dose mesenchymal stem cell (MSC) infusion ameliorates hyperglycemia but fails to restore normoglycemia in diabetic animals. We therefore hypothesized that multiple intravenous MSC infusions may reverse hyperglycemia in type 2 diabetes (T2D) rats. We administered serial allogenous bone-marrow derived MSC infusions (1 × 10(6)cells/infusion) via the tail vein once every 2 weeks to T2D… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 31 extracted citations

Stem cell transplantation improves aging-related diseases

Front. Cell Dev. Biol. • 2014
View 3 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 32 references

Immunometabolism: an emerging frontier

Nature Reviews Immunology • 2011
View 1 Excerpt

Shoelson , Immunometabolism : an emerging frontier

S. E. D. Mathis
Nat . Rev . Immunol . • 2011

Similar Papers

Loading similar papers…