Multiple intracellular pathways for regulation of chloride secretion in cultured pig tracheal submucosal gland cells.
@article{Zhang1999MultipleIP,
title={Multiple intracellular pathways for regulation of chloride secretion in cultured pig tracheal submucosal gland cells.},
author={A L Zhang and Godfried M. Roomans},
journal={The European respiratory journal},
year={1999},
volume={13 3},
pages={
571-6
}
}Tracheal submucosal glands are of great relative importance in the secretion of chloride and water to the airway lumen. This study aimed to examine whether the cystic fibrosis transmembrane conductance regulator (CFTR) is involved in cyclic adenosine monophosphate (cAMP) or Ca2+-activated Cl- secretion. Regulation of Cl- secretion in cell cultures derived from pig tracheal submucosal gland acini was investigated by X-ray microanalysis. With or without preincubation with CFTR antisense…
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