Multiple interactions between the ESCRT machinery and arrestin-related proteins: implications for PPXY-dependent budding.


Late domains are short peptide sequences encoded by enveloped viruses to promote the final separation of the nascent virus from the infected cell. These amino acid motifs facilitate viral egress by interacting with components of the ESCRT (endosomal sorting complex required for transport) machinery, ultimately leading to membrane scission by recruiting… (More)
DOI: 10.1128/JVI.02045-10