Multiple hormones stimulate the production of somatomedin by cultured human fibroblasts.

@article{Clemmons1984MultipleHS,
  title={Multiple hormones stimulate the production of somatomedin by cultured human fibroblasts.},
  author={David Robert Clemmons},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1984},
  volume={58 5},
  pages={850-6}
}
Although immunoreactive somatomedin (IR-SM) secretion by cultured human fibroblasts has been reported, the hormonal control of IR-SM production is not well defined. This study concerns the effects of several hormones and growth factors on IR-SM production by cultured human fibroblasts. Platelet-derived growth factor (PDGF) and fibroblast growth factor (FGF) had concentration-dependent stimulatory effects on IR-SM production when added to confluent quiescent cultures. When PDGF, FGF, macrophage… CONTINUE READING

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