Multiple genetically engineered humanized microenvironments in a single mouse

@inproceedings{Lee2016MultipleGE,
  title={Multiple genetically engineered humanized microenvironments in a single mouse},
  author={Jungwoo Lee and Dirk Heckl and Biju Parekkadan},
  booktitle={Biomaterials research},
  year={2016}
}
BACKGROUND Immunodeficient mouse models that accept human cell and tissue grafts can contribute greater knowledge to human stem cell research. In this technical report, we used biomaterial implants seeded with genetically engineered stromal cells to create several unique microenvironments in a single mouse. The scope of study was focused on human CD34… CONTINUE READING