Multiple food hypersensitivity as a cause of refractory chronic constipation in adults

  title={Multiple food hypersensitivity as a cause of refractory chronic constipation in adults},
  author={Antonio Carroccio and Lidia Di Prima and Giuseppe Iacono and Ada Maria Florena and Francesco D'Arpa and Carmelo Scium{\'e} and Angelo B. Cefal{\`u} and Davide Noto and Maurizio Rocco Averna},
  journal={Scandinavian Journal of Gastroenterology},
  pages={498 - 504}
Chronic constipation that is unresponsive to laxative treatment is a severe illness, but children unresponsive to laxatives have been successfully treated with an elimination diet. [] Key Method Four patients with refractory constipation who were unresponsive to high doses of laxatives were put on an oligo-antigenic diet and underwent successive double-blind, placebo-controlled, food challenges (DBPFC).

Food hypersensitivity as a cause of rectal bleeding in adults.

  • A. CarroccioG. Iacono G. Di Fede
  • Medicine
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • 2009

Colonic lymphoid nodular hyperplasia in children: relationship to food hypersensitivity.

  • G. IaconoA. Ravelli A. Carroccio
  • Medicine
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • 2007

Cows’ Milk Allergy-Associated Constipation: When to Look for It? A Narrative Review

A 4-week cows’ milk protein elimination diet may be considered for children with chronic constipation resistant to conventional treatment and who lack alarm sign/symptoms of organic diseases, and in subjects with ameliorated symptoms on CMP elimination, the diagnosis of CMA should be confirmed by a food challenge to avoid an unnecessary protracted diet.

Oligo-Antigenic Diet in the Treatment of Chronic Anal Fissures. Evidence for a Relationship Between Food Hypersensitivity and Anal Fissures

An oligo-antigenic diet combined with medical treatment improved the rate of chronic AF healing, and in more than 20% of the patients receiving medical and dietary treatment, AFs recurred on DBPC food challenge.

Nutrients and Constipation : Cause or Cure ?

The concept of inadequate dietary fiber intake has assumed a place of prominence as the etiology of constipation among both the lay population and physicians.

Colon in Food Allergy

The benign clinical course and the spontaneous resolution in most infants suggest the need for further prospective studies to validate markers that allow the identification of those children needing a dietary approach, and it remains to be assessed whether lymphoid nodular hyperplasia of the colon is a manifestation of food allergy.

Colonic lymphoid nodular hyperplasia in an adolescent.

The extensive LNH in the colon of an adolescent patient who experienced severe constipation and EDS type III is described.

Clinical symptoms in celiac patients on a gluten-free diet

Persistent intestinal villous atrophy in CD patients on a GFD is associated with gastrointestinal symptoms considered “atypical” for CD and not present at CD diagnosis.

Nutrients and Constipation: Cause or Cure? NUTRITION ISSUES IN GASTROENTEROLOGY, SERIES #61

Modification of diet has been touted as a cure-all for constipation, but the evidence base in support of this is weak and some suggested modifications,such as increased fiber intake, may be counterproductive in some patients, and others, such as the use of probiotics or prebiotics, lack much scientific evidence of efficacy.

Non-Celiac Wheat Sensitivity as an Allergic Condition: Personal Experience and Narrative Review

Patients with NCWS and multiple food sensitivity show several clinical, laboratory, and histological characteristics that suggest they might be suffering from non-immunoglobulin E (IgE)-mediated wheat allergy, however, other pathogenic mechanisms need to be considered.



Chronic constipation and food intolerance: A model of proctitis causing constipation

Food intolerance-related constipation is characterized by proctitis with eosinophil infiltrate of the rectal mucosa, and a reduced mucus gel layer can be considered a contributory factor in the pathogenesis of the constipation.

Chronic constipation as a symptom of cow milk allergy.

Food elimination based on IgG antibodies in irritable bowel syndrome: a randomised controlled trial

Food elimination based on IgG antibodies may be effective in reducing IBS symptoms and is worthy of further biomedical research.

Epidemiology of colonic symptoms and the irritable bowel syndrome.

Irritable bowel syndrome in the general population.

Symptoms consistent with a diagnosis of irritable bowel syndrome are present in almost one quarter of the general population and tend to be associated with a number of other complaints and conditions, some of which may reflect smooth muscle dysfunction.

CASE REPORT: Autoimmune Enteropathy and Colitis in an Adult Patient

A case of generalized gut disorder in an adult patient, affecting both the small intestine and the colon and characterized by the presence of circulating anti-enterocyte autoantibodies is reported.

Epidemiology of constipation (EPOC) study in the United States: relation of clinical subtypes to sociodemographic features

Differences in epidemiological profile by age, sex ratio, and relation to other sociodemographical factors support the distinction of two and possibly more symptom-based subtypes of constipation.

Isolated rice intolerance: clinical and immunologic characteristics in four infants.

Gastroesophageal reflux and cow's milk allergy in infants: a prospective study.

Immunologic and absorptive tests in celiac disease: can they replace intestinal biopsies?

The authors conclude that the absorption tests cannot be used successfully in screening for celiac disease, owing to their low specificity and would advise their use combined with AGA to obtain a sensitivity and specificity of 100.