Multiple folate transport systems in L1210 cells.

  title={Multiple folate transport systems in L1210 cells.},
  author={J G Fan and K S Vitols and F. M. Huennekens},
  journal={Advances in enzyme regulation},
Biotin derivatives of methotrexate (biotin-SS-MTX) and folate (biotin-SS-folate), in which the functional components are joined by a dissociable disulfide-containing spacer, have been synthesized, purified by DEAE-Trisacryl chromatography, and characterized by HPLC, elemental analysis and mass spectrometry. These compounds provide a convenient means for the… CONTINUE READING