Multiple factors contribute to the pathogenesis of hypertension in Cushing's syndrome.

@article{Saruta1986MultipleFC,
  title={Multiple factors contribute to the pathogenesis of hypertension in Cushing's syndrome.},
  author={Takao Saruta and Hiromichi Suzuki and Masashi Handa and Yasuo Igarashi and Kazunao Kondo and Shigetoshi Senba},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1986},
  volume={62 2},
  pages={275-9}
}
The mechanisms causing high blood pressure in patients with Cushing's syndrome were investigated by measurements of humoral factors and pharmacological maneuvers. Twelve patients with adrenal adenomas were studied. The mean systolic and diastolic pressures of the patients were 171 +/- 28 and 109 +/- 15 mm Hg (+/- SEM), respectively, which were significantly higher than those of normal subjects. PRA, plasma renin concentration, plasma renin substrate, plasma cortisol, plasma aldosterone, urinary… CONTINUE READING